Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ppargc1a  peroxisome proliferative activated receptor, gamma, coactivator 1 alpha   (Synonyms: A830037N07Rik, Gm11133, Pgc1, Pgc-1alpha, Pgc-1alphaa, Pgco1, PPAR Gamma Coactivator-1)
Results	Reference
1	J:271356 Dai N, Zhao L, Wrighting D, Kramer D, Majithia A, Wang Y, Cracan V, Borges-Rivera D, Mootha VK, Nahrendorf M, Thorburn DR, Minichiello L, Altshuler D, Avruch J, IGF2BP2/IMP2-Deficient mice resist obesity through enhanced translation of Ucp1 mRNA and Other mRNAs encoding mitochondrial proteins. Cell Metab. 2015 Apr 7;21(4):609-21
1	J:330579 Gambarotto L, Metti S, Chrisam M, Cerqua C, Sabatelli P, Armani A, Zanon C, Spizzotin M, Castagnaro S, Strappazzon F, Grumati P, Cescon M, Braghetta P, Trevisson E, Cecconi F, Bonaldo P, Ambra1 deficiency impairs mitophagy in skeletal muscle. J Cachexia Sarcopenia Muscle. 2022 Aug;13(4):2211-2224
1	J:326089 Ghnaimawi S, Zhang S, Baum JI, Huang Y, The Effects of Maternal Intake of EPA and DHA Enriched Diet During Pregnancy and Lactation on Offspring's Muscle Development and Energy Homeostasis. Front Physiol. 2022;13:881624
1	J:236559 Hasegawa K, Yasuda T, Shiraishi C, Fujiwara K, Przedborski S, Mochizuki H, Yoshikawa K, Promotion of mitochondrial biogenesis by necdin protects neurons against mitochondrial insults. Nat Commun. 2016 Mar 14;7:10943
1	J:137598 Lai L, Leone TC, Zechner C, Schaeffer PJ, Kelly SM, Flanagan DP, Medeiros DM, Kovacs A, Kelly DP, Transcriptional coactivators PGC-1{alpha} and PGC-l{beta} control overlapping programs required for perinatal maturation of the heart. Genes Dev. 2008 Jul 15;22(14):1948-61
1*	J:333645 Lau J, Shi YC, Herzog H, Temperature dependence of the control of energy homeostasis requires CART signaling. Neuropeptides. 2016 Oct;59:97-109
1	J:307395 Mirra S, Garcia-Arroyo R, B Domenech E, Gavalda-Navarro A, Herrera-Ubeda C, Oliva C, Garcia-Fernandez J, Artuch R, Villarroya F, Marfany G, CERKL, a retinal dystrophy gene, regulates mitochondrial function and dynamics in the mammalian retina. Neurobiol Dis. 2021 Aug;156:105405
1	J:100019 Oh M, Rybkin II, Copeland V, Czubryt MP, Shelton JM, van Rooij E, Richardson JA, Hill JA, De Windt LJ, Bassel-Duby R, Olson EN, Rothermel BA, Calcineurin is necessary for the maintenance but not embryonic development of slow muscle fibers. Mol Cell Biol. 2005 Aug;25(15):6629-38
1	J:333724 Park EJ, Kim HS, Lee DH, Kim SM, Yoon JS, Lee JM, Im SJ, Lee H, Lee MW, Lee CW, Ssu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation. Nat Commun. 2023 Feb 25;14(1):1097
1	J:154380 Seo J, Fortuno ES 3rd, Suh JM, Stenesen D, Tang W, Parks EJ, Adams CM, Townes T, Graff JM, Atf4 regulates obesity, glucose homeostasis, and energy expenditure. Diabetes. 2009 Nov;58(11):2565-73
1	J:247178 Singh R, Braga M, Reddy ST, Lee SJ, Parveen M, Grijalva V, Vergnes L, Pervin S, Follistatin Targets Distinct Pathways To Promote Brown Adipocyte Characteristics in Brown and White Adipose Tissues. Endocrinology. 2017 May 01;158(5):1217-1230
1	J:241230 Spitler KM, Ponce JM, Oudit GY, Hall DD, Grueter CE, Cardiac Med1 deletion promotes early lethality, cardiac remodeling, and transcriptional reprogramming. Am J Physiol Heart Circ Physiol. 2017 Apr 01;312(4):H768-H780
1*	J:294247 Wang J, Yun Q, Qian JJ, Song HR, Wang L, Inkabi SE, Xu RJ, Hu YM, Zhang WN, Einat H, Mice Lacking the Transcriptional Coactivator PGC-1alpha Exhibit Hyperactivity. Neuropsychobiology. 2019;78(4):182-188
1	J:337787 Wang Y, Li X, Liu C, Zhou L, Shi L, Zhang Z, Chen L, Gao L, Xu Y, Huang H, Li J, Chen Z, WTAP regulates postnatal development of brown adipose tissue by stabilizing METTL3 in mice. Life Metabolism. 2022;1(3):270-284
1	J:321746 Yu H, Zhang F, Yan P, Zhang S, Lou Y, Geng Z, Li Z, Zhang Y, Xu Y, Lu Y, Chen C, Wang D, Zhu W, Hu X, Wang J, Zhuang T, Zhang Y, Wu G, Liu J, Zeng C, Pu WT, Sun K, Zhang B, LARP7 Protects Against Heart Failure by Enhancing Mitochondrial Biogenesis. Circulation. 2021;143(20):2007-2022